The example demonstrates how to use the RadAjaxManager control in a page->user control scenario.          You can use the same approach in a master->content page scenario.     
    The standard controls from this demo (RadTabStrip, RadMultiPage, DetailsView, RadGrids and controls inside them)         reside within a  WebUserControl and the manager is placed in the main page (Telerik support always recommends that).         You can apply exactly the same technique when the updated controls are hosted in a content page and the RadAjaxManager         is added on the relevant master page.     
    
    
        
            
                <
                telerik:RadAjaxManagerProxy
                ID
                =
                "AjaxManagerProxy1"
                runat
                =
                "server"
                >
            
        
        
            
                    
                
                    <
                    AjaxSettings
                    >
                
            
        
        
            
                        
                
                    <
                    telerik:AjaxSetting
                    AjaxControlID
                    =
                    "EmployeesGrid"
                    >
                
            
        
        
            
                            
                
                    <
                    UpdatedControls
                    >
                
            
        
        
            
                                
                
                    <
                    telerik:AjaxUpdatedControl
                    ControlID
                    =
                    "RadTabStrip1"
                    />
                
            
        
        
            
                                
                
                    <
                    telerik:AjaxUpdatedControl
                    ControlID
                    =
                    "RadMultiPage1"
                    LoadingPanelID
                    =
                    "RadAjaxLoadingPanel1"
                    />
                
            
        
        
            
                                
                
                    <
                    telerik:AjaxUpdatedControl
                    ControlID
                    =
                    "EmployeesGrid"
                    />
                
            
        
        
            
                            
                
                    </
                    UpdatedControls
                    >
                
            
        
        
            
                        
                
                    </
                    telerik:AjaxSetting
                    >
                
            
        
        
            
                        
                
                    <
                    telerik:AjaxSetting
                    AjaxControlID
                    =
                    "OrdersGrid"
                    >
                
            
        
        
            
                            
                
                    <
                    UpdatedControls
                    >
                
            
        
        
            
                                
                
                    <
                    telerik:AjaxUpdatedControl
                    ControlID
                    =
                    "OrdersGrid"
                    />
                
            
        
        
            
                            
                
                    </
                    UpdatedControls
                    >
                
            
        
        
            
                        
                
                    </
                    telerik:AjaxSetting
                    >
                
            
        
        
            
                    
                
                    </
                    AjaxSettings
                    >
                
            
        
        
            
                </
                telerik:RadAjaxManagerProxy
                >
            
        
     
    Should you need the server or client-side RadAjaxManager functionality (like ResponseScripts collection, ajaxRequest function) you can get the "master" manager instance via Server-Side GetCurrent         method from the user control code-behind:     
    
        
            
                RadAjaxManager.GetCurrent(
                this
                ).Alert(
                "1"
                );
            
        
     
    
    
        Use server-side code block in a JS function inside your WebUserControl to call the master manager ajaxRequest function:
    
    
        
            
                <telerik:RadCodeBlock ID=
                "RadCodeBlock1"
                runat=
                "server"
                >
            
        
        
            
                    
                
                    <script type=
                    "text/javascript"
                    >
                
            
        
        
            
                        
                
                    function
                    myUserControlClickHandler()
                
            
        
        
            
                        
                
                    {
                
            
        
        
            
                            
                
                    $find(
                    "<%= RadAjaxManager.GetCurrent(this).ClientID %>"
                    ).ajaxRequest(
                    "content"
                    );
                
            
        
        
            
                        
                
                    }
                
            
        
        
            
                    
                
                    </script>
                
            
        
        
            
                </telerik:RadCodeBlock>